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Lovegra vs Addyi (Flibanserin): What Is More Effective for Women?

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Category : News

Indian Lovegra in a Few Words

How does it function?

lovegraThe action of female Lovegra in physiological aspect is based on the impact of PDE5 inhibitor that helps to increase the level of blood circulation in vascular system of female pelvic organs. Active action of nitrogen oxide expands smooth muscle cells of arteries and fills the labia and clitoris with a large amount of blood. Moreover, a woman feels an increase in the functionality of mucous glands starting a strong lubrication process in vagina. Breasts plump up and become firm and elastic; there is a perceptible blush on cheeks, and a woman feels the rush of strength and energy. Then the level of arousal starts to increase and there is an urgent need for sexual contact. Lovegra is the best way to combat sexual dysfunction in the representatives of the beautiful half of humanity.

Application method

The action of Lovegra begins within 30-40 minutes after administration and lasts up to 5-6 hours. Daily dose must not exceed 100 mg of active ingredient (1 tablet per day). If necessary, a lady can reduce the dose to 25 mg (if there are a number of contraindications or some side-effects were experienced) or increase it to 150 mg (if the effect has minimal manifestation). Tablets are taken orally and drunk with a glass of water. It is not recommended to use Lovegra along with alcohol and fatty, salty, spicy or overly sweet food. The dosage of Lovegra must not be exceeded without particular necessity or prior consultation by a specialist. Self-medication and uncontrolled use of the medicine are prohibited.

Discover more about medications for women: L-Dopa, Lovegra and Female Viagra to Chemically Boost Her Desire

Indications for use

Lovegra is prescribed to those women who have the following conditions:

  • regular manifestations of sexual dysfunction in the body;
  • prolonged experience of orgasmic disorders;
  • complete or partial impairment of  sexual attraction to a man;
  • malfunction of reproductive or genitourinary systems;
  • dissatisfaction with sexual relations with a partner;
  • absence of sexual drive and desire to initiate sex;
  • inflammation, acute soreness or severe dryness in vaginal opening;
  • short sexual intercourse;
  • constant irritation, apathy, drowsiness;
  • nervous or stressful state;
  • complete absence of pleasant sensations when orgasm is achieved;
  • a negative reaction to sexual arousal.

Before starting to use the drug, it is advisable to undergo a clinical examination by an attending physician.

Composition

Lovegra is produced in India in the form of tablets that have the shape of a diamond and are covered with a safe red coating. One blister contains 4 tablets of Lovegra. The active substance making a woman’s reproductive system work is sildenafil citrate. This component is found in tablets equivalent to 100 milligrams of sildenafil. In the meantime, Lovegra consists of the following substances: calcium hydrogenphosphate, crystalline cellulose, sodium carmellose, magnesium stearate, lactose and triacetin. The use of all elements is safe and clinically proven.

Contraindications

Pregnant and lactating women are not allowed to take Lovegra. The results or its use in these cases can be the most deplorable. Treatment with Lovegra can cause significant harm to an undeveloped fetus and cause genetic abnormalities. If you do not want to harm your child, it is recommended to refuse Lovegra application for this period.

Lovegra should be taken with caution by those patients who have renal and hepatic diseases, cancer, heart disease, low or high blood pressure, peptic ulcer and anatomical deformations of vagina. Also, the drug is contraindicated to children and girls who have not reached adulthood. Usually it is not prescribed to patients who are completely contraindicated to have sexual activity for any reason. Viagra is contraindicated to women who are currently taking nitrogen oxide donors. To exclude the possibility of an acute form of side-effects, a lady should conduct an additional sensitivity analysis to the medicinal substances added to the drug.

Possible side-effects

Before passing the course of treatment with this drug, a woman should undergo a qualified examination by her attending doctor. In order to avoid the occurrence of adverse side-effects from the use of Lovegra, a specialist must identify the patient’s individual intolerability to any component of the drug, including sildenafil citrate.

Overdose

Lovegra was subjected to various experiments and studies resulting from which it was found out that the drug is indicative to women having severe sexual disorders. To date, the remedy continues to be tested. Cases of an overdose of Lovegra were not identified. However, with occurrence of the slightest symptoms of side-effects, a woman should immediately stop taking the medication, if possible, rinse the stomach with a weak solution of potassium permanganate and contact a medical center. Self-medication and subsequent application of tablets are strictly prohibited. Incorrect or untimely treatment can lead to development of more serious diseases.

Flibanserin Summary

Addyi development

The drug Addyi (flibanserin) was officially launched in the United States. This means that all women with a hypoactive disorder of sexual desire are able to adjust their sex life by means of this magic remedy. The Food and Drug Administration (FDA) approved the production of Addyi with only the fourth attempt. Sprout Pharmaceuticals Inc. was trying to launch a project to produce flibanserin back in 2010, but at that time the effect of the drug was not clinically proven. And then the pharmacists went to the trick. Along with the best marketers, they launched the campaign with the slogan proclaiming that there are twenty-six official drugs for male impotency, whereas there are none of them for female sexual disorders. The motto “26-0 in favor of men” allowed the producers of flibanserin to exert pressure on the public. Masterfully having played a card of sexual discrimination of women, Sprout Pharmaceuticals Inc received powerful support from various legal organizations. After numerous petitions and lobbying of politicians on this issue the production of the drug was approved from the fourth attempt.

How does flibanserin work?

In order to understand the way this drug works, first it is important to find out the meaning of a hypoactive disorder of sexual desire. So, if the incomprehensible scientific terminology is avoided, low sexual desire of a woman is the result of a malfunction or imbalance in the production of hormones and mediators. Sexual function requires a complex interaction of several neurotransmitters and hormones, both centrally and peripherally. Sexual desire is considered as a result of a complex balance between suppressive and stimulating signals in cerebrum. For example, the hormones dopamine, estrogen, progesterone and testosterone play an exciting role, while prolactin and serotonin act as inhibitors (or suppressors).

Flibanserin is a multifunctional agonist-antagonist of serotonin capable of restoring sexual desire by affecting the prefrontal cortex of brain. Therefore, flibanserin acts by increasing the level of neurotransmitters dopamine and norepinephrine in the prefrontal cortex, and by reducing the action of serotonin.

Was flibanserin ever tested?

Since the first attempts to start the project, the company Sprout Pharmaceuticals (official website sproutpharma.com) Inc conducted a large-scale, randomized, placebo-controlled trials that involved 2400 women of pre- and post- menopause (average age was 36 years). Women who took 100 mg of flibanserin reported a slight increase in sexual desire. At the same time, according to the results in the North American group of volunteers, the number of ‘sexually satisfying cases’ increased from 2,7 to 4,6 during the test period, as opposed to placebo . These data were enough to convince the FDA that Addyi is indeed effective, despite the side-effects among which the most common were nausea, dizziness, fatigue, drowsiness, insomnia, dry mouth, hypotension, low blood pressure and even loss of consciousness during orgasm. The latter effect was particularly pronounced when the drug was administered with alcohol.

Despite the numerous critical opinions, flibanserin is set into production. However, by the decision of the FDA, Sprout Pharmaceuticals Inc is required to conduct a study to further assess health risks associated with the interaction of flibanserin with alcohol. In the United States, the drug is available for women only after prescription from certified health professionals and certified pharmacies depending on the availability of health insurance.

What does a woman feel after Addyi application?

The effective dosage of flibanserin is 100 mg. Administration is carried out within a month once a day before bedtime. When taking female Viagra, dopamine is released in blood, and the level of estrogen and testosterone elevates which results in increase of sexual activity and attraction. Under the action of the drug blood circulation in genital area increases and blood flow into pelvic organs gets enhanced resulting in impact on sensory nerves located in erogenous zones. These nerve endings transmit impulses to spinal cord and brain faster and stronger. Producers assure that regular intake of the drug contributes to the development of vaginal secretion that allows a woman to reach a bright and strong orgasm.

Is It Possible to Put a Sign of Equality between Lovegra and Addyi (Flibanserin)?

First of all, the drugs are based on different active substances that affect diverse mechanisms in female body to ensure sexual drive. This is a critical discrepancy that is allows never put the equality mark between Lovegra and Addyi. These active substances cause difference side-effects and have particular contraindications.

Moreover, many experts are skeptical about the very definition of the drugs as “female Viagra”. Associate Professor of the University of Victoria in British Columbia believes that sexual problems of women during the menopause are less physiologically-oriented than men’s ones. Frigidity is caused by external factors, such as interpersonal relationships, necessity to make social decisions, pressure associated with characteristics of female sexuality, inferiority complexes, stress at work, etc. And it would be rather reckless to argue that the influence of all these factors can be leveled by taking one pill. No diagnostic test has revealed any biological links between brain-hormone-genital blood stream in women’s sexual problems. Low sexual desire in women reflects the difference in desire between the two partners, and it is unethical and unscientific to associate the differences in the couple’s desires solely with hormone deficiency in a woman during menopause. Viagra relieves men of erectile dysfunction short-term – this is a proven fact. However, there is no evidence that flibanserin or sildenafil is an antidote to lowered libido in women, since sexual desire is a more complex and amorphous condition than the mechanism of erection.

Sex, Drugs and the disease PERSPECTIVE

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Category : Womens Issues

1da77334cd9311401d65e5be4ad5817aDrugs (medically prescribed, alcohol, nicotine, caffeine, illicit drugs) are consumed to cure, to calm, to stimulate, or to avoid physical and psychological pain. The body affected by drugs is a body with altered sexual responsiveness. Therefore, ingested drugs must be recognized as possible causes of sexual dysfunctions and disorders.

Some drugs are alleged to be prosexual in that they are thought to promote sexual activity. Alcohol, cocaine, and hallucinogens, including amphetamines, fall into this grouping. Alcohol is popularly thought to decrease inhibitions about sexual activity. In fact, several researchers over the decades have generally concluded that alcohol has negative physiological effects on arousal and orgasm, to say nothing of the severe health effects that can result from sustained alcohol abuse. But the expectations of both women and men are such that they report increased sexual functioning, even when responding to an alcohol placebo. Thus, the frequent clinical situation is that patients generally believe that alcohol helps them to function sexually, while in fact both its short-term and long-term effects on healthy sexual functioning may be the opposite.

Cocaine is a drug of abuse that is often linked with sexual behavior. As is often the case with alcohol intoxication, cocaine impairs judgment and often leads to sexual activity that puts individuals at risk for sexually transmitted diseases. Cocaine’s dopaminergic effect increases sexual desire in both men and women but also inhibits orgasm and, given a sufficient dosage, causes erectile dysfunction. Individuals with a cocaine habit will find themselves with increased sexual desire, with little inhibition about the sexual activity, and eventually unable to become aroused.

Hallucinogens such as LSD, Ecstasy, mushrooms, and amphetamines are commonly perceived to be aphrodisiac in their effect on sexual function. This might be expected given the CNS effects caused by these substances. As Crenshaw and Goldberg noted, “The intoxicated states (however mystical) that occur with hallucinogens involve severe alterations in dopamine, serotonin and excitatory amino acid activity. Phencyclidine (PCP, angel dust), for example, incites potent activity at glutamate receptors, apparently inducing psychoses by altering excitatory amino acids.

Other drugs are decidedly negative in their effects on sexual functioning. Excessive alcohol, chronic nicotine use that has caused cardiovascular disease, some antihypertensives, and many antidepressants—all have been implicated in interfering with sexual function. Table lists some of the more commonly prescribed drugs and their effects on sexual function. This not an exhaustive list, but it provides examples of the reported sexual dysfunctions associated with the drugs.

Given the various effects that drugs can have on the physiological basis of sexual function, the clinician needs to know what drugs the individual with a sexual problem is taking. A complete review of a patient’s use of prescribed, over-the-counter, and possible illegal drugs is essential. Once known, the drugs should be examined for their possible contributory role in the sexual problem. But if you need treatment erectile dysfunction you can use Generic Viagra in Australia – it have low cost and can amaze you and your friend. Viagra with medical component Sildenafil can work wonders in Your Sexual Life. In our store you can purchase female viagra to increase sexual desire in women by first pill.